What are the characteristics of p-chloro-m-xylenol?

In order to study the biological effect of compound disinfectant of p-chloro-m-xylenol, its germicidal efficacy and toxicity were observed by quantitative germicidal test and animal experiment. Results when the compound disinfectant containing p-chloro-m-xylenol 1629 mg / L acted for 1.5 min, the logarithm values of killing Pseudomonas aeruginosa and Candida albicans in suspension were above 5.0 and 4.0 respectively, The killing logarithm of the compound disinfectant to Escherichia coli and Staphylococcus aureus was more than 5.0 after 10 min. it was practically non-toxic. No abnormal changes were found in the subacute toxicity test. The disinfectant containing 814 mg / L p-chloro-m-xylenol had no irritation to the skin of rabbits, but 312 mg / L. conclusion the compound disinfectant has good killing effect on bacterial propagules and fungi, with little irritation and low toxicity

Performance characteristics of p-chloro-m-xylenol:

(1) Solubility: 20 ℃ water solution: 0.03% w / V; 20 ℃ 95% ethanol: 50% w / V; soluble in PEG, PVA, olefin, benzene, ether, nonvolatile oil and strong alkali water solution.

(2) Antibacterial activity: it has excellent killing effect on Gram positive and negative bacteria and mold.

(3) Safety: acute oral dose: LD50 ≥ 3G / kg (mice); acute injection dose: LD50 ≥ 2G / kg (mice).

(4) Stability: PCMX has good stability under normal storage conditions and will not be inactivated.